Primary structure and functional expression of a cyclic nucleotide-gated channel from rabbit aorta.

نویسندگان

  • M Biel
  • W Altenhofen
  • R Hullin
  • J Ludwig
  • M Freichel
  • V Flockerzi
  • N Dascal
  • U B Kaupp
  • F Hofmann
چکیده

Sequences specific for cyclic nucleotide-gated channels (CNG channels) have been amplified by PCR from cDNA of heart, aorta, sino-atrial node, cerebellum, C-cells and kidney. The complete amino acid sequence of a CNG channel from rabbit aorta has been deduced by cloning and sequence analysis of the cDNA. Synthetic RNA derived from this cDNA induces the formation of a functional CNG channel in Xenopus oocytes.

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عنوان ژورنال:
  • FEBS letters

دوره 329 1-2  شماره 

صفحات  -

تاریخ انتشار 1993